EPOR anticorps (Middle Region)

N° du produit ABIN952118

L’anticorps Lapin Polyclonal anti-EPOR a été validé pour WB, FACS et EIA. Il convient pour détecter EPOR dans des échantillons de Humain.

Aperçu rapide pour EPOR anticorps (Middle Region) (ABIN952118)

Antigène: EPOR (Erythropoietin Receptor (EPOR))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EPOR est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)

Détail du produit anti-EPOR anticorps

Épitope: AA 328-357, Middle Region

Specificité: This antibody recognizes Human Erythropoietin receptor (Center).

Purification: Affinity Chromatography on Protein A

Immunogène: KLH conjugated synthetic peptide between 328-357 amino acids from the Central region of Human Erythropoietin receptor Genename: EPOR

Isotype: Ig Fraction

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur EPOR

Antigène: EPOR (Erythropoietin Receptor (EPOR))

Autre désignation: Erythropoietin Receptor

Sujet: This gene encodes the erythropoietin receptor which is a member of the cytokine receptor family. Upon erythropoietin binding, this receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis. Dysregulation of this gene may affect the growth of certain tumors. Alternate splicing results in multiple transcript variants.Synonyms: EPO-R, EPOR

Poids moléculaire: 55065 Da

ID gène: 2057

NCBI Accession: NP_000112

Pathways: Signalistation JAK/STAT